RES: [AF] Prolactina e ISRSS

[Wellington Barros da Silva]

Manolo,
 
Segue informação que talvez seja útil
Wessels-van Middendorp AM, Timmerman L. <http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=16956087&ordinalpos=7&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum>  Galactorrhoea and the use of selective serotonin reuptake inhibitors. Tijdschr Psychiatr. 2006;48(3):229-34

Abstract: "The subject of this case study is a female patient who was treated with a selective serotonin reuptake inhibitor (SSRI), citalopram, because of a depressive episode. She developed symptoms of galactorrhea; there was a time relationship between suspension of the treatment with citalopram and a reduction of the galactorrhea symptoms. The consulting internist assumed that the symptoms were due to hyperprolactinemia arising from under-supplementation of thyroid hormone and resultant hypothyroidism. Psychiatrists usually see galactorrhea in patients who are taking antipsychotics. However, few psychiatrists know that galactorrhea can also be caused by SSRIs. When a patient has symptoms of bilateral galactorrhea and has used an SSRI and when hyperprolactinemia has been found in laboratory tests it is probably advisable to stop the SSRI medication"
 
Adicionalmente envio a você um relato publicado em Actas Españolas de Psiquiatría, 29(6): 414, 2001
 
Há uma informação na Revista de Psiquiatria Clínica sobre possíveis mecanismos que explicariam a
elevação de prolactina
<http://www.scielo.br/scielo.php?pid=S0101-60832004000200003&script=sci_arttext&tlng=pt> <http://www.scielo.br/scielo.php?pid=S0101-60832004000200003&script=sci_arttext&tlng=pt>
 
Espero que tenha ajudado
 
Prof. Wellington Barros da Silva (Farm.M.C.Farm.)
Universidade Católica de Brasília