[AF] ¿tratar una lumbalgia con Ab?

[Pedro del Río Pérez]

Antibiotic treatment in patients with chronic low back pain
and vertebral bone edema (Modic type 1 changes): a
double-blind randomized clinical controlled trial of efficacy.

Eur Spine J (2013) 22:697–707
DOI 10.1007/s00586-013-2675-y

<http://www.ovingclinic.co.uk/wordpress/wp-content/uploads/2013/05/Eur-Sp-J-Albert-Modic-2013.pdf>

Parece que mal no les ha ido. Amoxi/Clavu 500/125 mg /8 h/100 días.

Conclusions
In this double-blind RCT patients with CLBP and Modic type
1 change (bone edema) following a lumbar disc herniation,
who were treated with antibiotics obtained statistically significant
improvements compared to the placebo group in all
measured parameters, including: the primary outcome of
disease-specific disability, back pain intensity, and the
secondary outcomes of, leg pain intensity, general improvement,
number of hours with pain, reduced number with chronic
pain, physical examination tests, and MRI Modic grading.
Only four participants (2.8 %) stopped treatment due to side
effects, which were mostly gastroenterointestinal.
For the primary outcome measures, the effect size was
clinically important in magnitude and substantially greater
than all currently established treatments.
Antibiotics could be considered as a treatment option for
this special subgroup of patients with CLBP and Modic
type 1 changes after a lumbar disc herniation when all other
treatment options have failed. More confirmatory work in
other populations and studies on improved protocols as
well as the background science should be encouraged.

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Saludos
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Pedro del Río Pérez
León
pedrodelrio en uninet.edu
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