[AF] Estatinas y mialgias.

José Daniel Carballeira Rodríguez jdcarballeira en gmail.com
Mie Mayo 20 13:21:48 CEST 2015

https://www.rnzcgp.org.nz/assets/documents/Publications/JPHC/June-2013/JPHCPotionPoisonJune2013.pdf <https://www.rnzcgp.org.nz/assets/documents/Publications/JPHC/June-2013/JPHCPotionPoisonJune2013.pdf>

"There are no Cochrane Database Systematic Reviews (CDSR) reporting the clinical efficacy of coenzyme Q10 in statin-associated myopathy. Coenzyme Q10 is generally well tolerated. A systematic review suggests that rather than hypothesising about potential clinical benefits, large clinical studies are required to allow robust systematic review. Further, there is insufficient evidence to recommend the routine administration of concomitant coenzyme Q10 for prevention of statin-associated myopathy.”

No hay evidencia suficiente recomendarla (a 6-2013 )

2015 http://www.ncbi.nlm.nih.gov/pubmed/25440725 <http://www.ncbi.nlm.nih.gov/pubmed/25440725>   "The results of this meta-analysis of available randomized controlled trials do not suggest any significant benefit of CoQ10 supplementation in improving statin-induced myopathy. Larger, well-designed trials are necessary to confirm the findings from this meta-analysis.”

De momento sin evidencia, hasta donde puedo ver


J.D. Carballeira

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