[AF] Cerivastatina y farmacovigilancia en JAMA

[Martín Cañás]

Estimadas y estimados colisteros 
para leer y analizar..
El JAMA publica en forma adelantada online una serie de artículos que evalúan  los datos referentes a las reacciones adversas la cerivastatina, retirada en el 2001, los conflictos de interés en el análisis de los datos y a propósito del tema un análisis de vigilancia poscomercialización
Los artículos seran publicados en el número del 1 de dicembre,  e incluyen entre otros a autores como Psaty, Rennie, DeAngelis y Brian Strom.
Los artículos y sus correspondientes hipervinculos son

David J. Graham, MD, MPH; Judy A. Staffa, PhD; Deborah Shatin, PhD; Susan E. Andrade, ScD; Stephanie D. Schech, MPH; Lois La Grenade, MD, MPH; Jerry H. Gurwitz, MD; K. Arnold Chan, MD, ScD; Michael J. Goodman, PhD; Richard Platt, MD, MSc  
Incidence of Hospitalized Rhabdomyolysis in Patients Treated With Lipid-Lowering Drugs JAMA. 2004;292:(DOI 10.1001/jama.292.21.2585). 
http://jama.ama-assn.org/cgi/content/full/292.21.2585v1



Bruce M. Psaty, MD, PhD; Curt D. Furberg, MD, PhD; Wayne A. Ray, PhD; Noel S. Weiss, MD, DrPH 
Potential for Conflict of Interest in the Evaluation of Suspected Adverse Drug Reactions. Use of Cerivastatin and Risk of Rhabdomyolysis .JAMA. 2004;292:(DOI 10.1001/jama.292.21.2622). 
http://jama.ama-assn.org/cgi/content/full/292.21.2622v1

Joseph D. Piorkowski, Jr, DO, JD, MPH 
Bayer's Response to "Potential for Conflict of Interest in the Evaluation of Suspected Adverse Drug Reactions: Use of Cerivastatin and Risk of Rhabdomyolysis" JAMA. 2004;292:(DOI 10.1001/jama.292.21.2655). 
http://jama.ama-assn.org/cgi/content/full/292.21.2655v1

Bruce M. Psaty, MD, PhD; Curt D. Furberg, MD, PhD; Wayne A. Ray, PhD; Noel S. Weiss, MD, DrPH  
Authors' Reply to Bayer's Response to "Potential for Conflict of Interest in the Evaluation of Suspected Adverse Drug Reactions: Use of Cerivastatin and Risk of Rhabdomyolysis" JAMA. 2004;292:(DOI 10.1001/jama.292.21.2658). 

http://jama.ama-assn.org/cgi/content/full/292.21.2658v1

Brian L. Strom, MD, MPH  
Potential for Conflict of Interest in the Evaluation of Suspected Adverse Drug Reactions A Counterpoint  JAMA. 2004;292:(DOI 10.1001/jama.292.21.2643).
http://jama.ama-assn.org/cgi/content/full/292.21.2643v1

Phil B. Fontanarosa, MD; Drummond Rennie, MD; Catherine D. DeAngelis, MD, MPH  
Postmarketing Surveillance-Lack of Vigilance, Lack of Trust JAMA. 2004;292:(DOI 10.1001/jama.292.21.2647). 
http://jama.ama-assn.org/cgi/content/full/292.21.2647v1

Saludos,
Martín

Martín Cañás
Grupo Argentino Para el Uso racional del Medicamento (GAPURMED)
La Plata  (Argentina)
macanas en netverk.com.ar